Agents and compositions and methods utilizing same useful in...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2349434

A method of immunizing against plaque forming diseases using display technology is provided. The method utilizes novel agents, or pharmaceutical compositions for vaccination against plaque forming diseases which rely upon presentation of an antigen or epitope on a display vehicle. The method further includes agents, or pharmaceutical compositions for vaccination against plaque forming diseases, which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, disaggregation of plaques results from the immunization.

La présente invention concerne un procédé d'immunisation contre les maladies formant des plaques, au moyen d'une technique d'affichage. Ce procédé consiste à utiliser de nouveaux agents, ou des compositions pharmaceutiques servant à la vaccination contre les maladies formant des plaques, et à présenter un antigène ou un épitope sur un support d'affichage. Ledit procédé consiste en outre à utiliser des agents, ou des compositions pharmaceutiques pour la vaccination contre les maladies formant des plaques, et à présenter un anticorps, ou une portion active de cet anticorps, sur un support d'affichage. Qu'il s'agisse d'antigènes ou d'anticorps, la désagrégation des plaques résulte de l'immunisation.

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