A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/39 (2006.01) A61P 37/04 (2006.01) C07K 14/18 (2006.01) C07K 14/78 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2612151
The invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70 % with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent.
La présente invention concerne l'utilisation d'un polypeptide comprenant une séquence correspondant au domaine EDA de la fibronectine, un fragment dudit domaine EDA capable de se lier au récepteur TLR4, ou un variant dudit domaine EDA ou un fragment capable de se lier au récepteur TLR4 et présentant une homologie de plus de 70 % avec n'importe quelle forme ou n'importe quel fragment naturel du domaine EDA, dans l'élaboration d'un agent immunostimulateur. La présente invention concerne également les méthodes de production et les applications dudit agent.
Gorraiz Ayala Marta
Lasarte Sagastibelza Juan Jose
Leclerc Claude
Prieto Valtuena Jesus
Marks & Clerk
Proyecto de Biomedicina Cima S.l.
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