Agents and methods for modulation of zinc transfer by...

Details Agents and methods for modulation of zinc transfer by... Agents and methods for modulation of zinc transfer by...

A - Human Necessities

61

K

A61K 31/33 (2006.01) A61K 31/00 (2006.01) A61K 31/145 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/355 (2006.01) A61K 31/375 (2006.01) A61K 31/385 (2006.01) A61K 31/41 (2006.01) A61K 31/555 (2006.01) A61K 38/06 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2326771

A method is provided for the treatment of diseases of plants and animals where such diseases involve disturbance of zinc homeostasis. The method involves administration of therapeutic agents that after cellular oxidation potential so as to oxidize metallothionein and thereby release zinc ions, or as to maintain metallothionein in a reduced state so as to prevent transfer of zinc from metallothionein to zinc acceptors.

L'invention concerne un procédé destiné au traitement des maladies végétales et animales lorsque ces maladies impliquent un dysfonctionnement de l'homéostasie du zinc. Ledit procédé consiste à administrer des agents thérapeutiques modifiant le potentiel d'excitation cellulaire de manière à oxyder la métallothionéine, et donc à libérer des ions de zinc, ou de manière à maintenir la métallothionéine dans un état réduit pour empêcher le transfert du zinc de la métallothionéine aux accepteurs de zinc.

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