Agents containing imidazoline derivatives for systemic...

C - Chemistry – Metallurgy – 07 – D

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260/314.7, 167/9

C07D 233/20 (2006.01) A01N 43/50 (2006.01) C07D 233/22 (2006.01) C07D 233/24 (2006.01)

Patent

CA 2005976

Abstract of the disclosure: Agents containing imidazoline derivatives for systemic combating of ectoparasites in host animals and novel imidazoline derivatives The present invention relates to agents for systemic combating of ectoparasites in host animals, containing a compound of the formula I (I) Image in which R1 denotes hydrogen, (C1-C5)-alkyl, (C1-C3)-halo- genoalkyl or halogen; R2 and R3 independently of one another denote (C1-C5)- alkyl, (C2-Cs)-alkerLyl, (C2-C5)-alkynyl, (C3-C7)- cycloalkyl, (C3-C7)-cycloalkenyl, (C1-C3)-halo- genoalkyl, halogen, cyano, nitro, (C1-C5)- alkoxy, (C1-C3)-alkoxy-(C1-C3)-alkyl, (C1-C3)- halogenoalkoxy or (C1-C3)-alkylthio, or R2 and R3 together form a polymethylene chain having 2 to 5 carbon atoms; R4 denotes hydrogen, (C1-C10)-alkyl, (C2-C5)-alkenyl or (C3-C7)-cycloalkyl; R5 denotes hydrogen, (C1-C10)-alkyl, (C3-C5)-alk- enyl, (C3-C5)-alkynyl, (C3-C7)-cycloalkyl, (C3- C7)-cycloalkenyl, (C1-C3)-halogenoalkyl or (C1- C3 )-alkoxy-(C1-C3)-alkyl; X denotes oxygen, sulfur or an -NR6- group; and R6 denoteshydrogen, (C1-C5)-alkyl,(C3-C5)-alkenyl, (C3-C5)-alkynyl, (C3-C7)-cycloalkyl, (C3-C7)- cycloalkenyl, (C1-C3)-halogenoalkyl or (C1-C3)- alkoxy-(C1-C3)-alkyl, or biologically tolerated acid addition salts thereof. The compounds of the formula I are novel in some cases and are likewise included in the invention.

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