Agents directed against parasites of fishes and insects

Details Agents directed against parasites of fishes and insects Agents directed against parasites of fishes and insects

A - Human Necessities

01

N

167/216, 167/6.6

A01N 43/707 (2006.01) A61K 31/53 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01)

Patent

CA 2010196

- 1 - Abstract of the disclosure HOE 89/F 058K Agents directed against parasites of fishes and insects Compounds of the general formula (I) Image (I) in which R1 represents together with R2 a chemical bond or hydrogen, alkyl, cycloalkyl, benzyl which can be sub- stituted in the phenyl ring by halogen and alkyl, alkanoyl which can be substituted by halogen, or benzoyl which can be substituted by halogen and alkyl, R2 represents together with R1 a chemical bond or hydrogen, R3 represents hydrogen, alkyl or cycloalkyl, R4 represents hydrogen, alkyl, cycloalkyl, benzyl which can be substituted by halogen and alkyl, X1, X2, Y1, Y2 and Z represent, independently of one another, a) hydrogen, halogen, trifluoromethyl, alkyl, cyclo- alkyl, alkoxy, alkylthio, alkylsulfinyl, alkyl- sulfonyl, benzylthio, benzylsulfinyl, benzyl- sulfonyl, nitro, cyano, amino, alkylamino, dialkyl- amino, N-alkylaminoethyl, N,N-dialkylaminomethyl, piperidino, morpholino, thiomorpholino, 1-pyrroli- dinyl, 4-methyl-1-piperazinyl or acylamino or b) a phenoxy, phenylthio, phenylsulfinyl, phenyl- sulfonyl, benzoyl, benzoylamino, phenylamino, N,N- phenylalkylamino, 1-cyano-1-phenyl-methyl, 1-cyano- 1,1-diphenyl-methyl, 1-cyano-1-phenyl-1-(C1-C6- alkyl)-methyl, 1-cyano-1-phenyl-1-(C3-C6-cycloalkyl)- methyl, thienyl or naphthyl radical, each of which is unsubstituted or substituted a total of 1, 2 or - 2 - 3 times in the phenyl ring by radicals mentioned under a), or else their physiologically tolerated salts in the case where R4=H, are suitable even at low dosages for con- trolling a wide spectrum of endo- and ectoparasites of fishes or insects.

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