Agents for and method of quantifying binding

G - Physics – 01 – N

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G01N 33/96 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2552548

The present invention provides a presentation system and method of use for quantifying a target moiety in a sample which may contain the target moiety, the method comprising using a specified concentration or varying the concentration of a presentation system in order to generate a comparison point or calibration curve which provides means for comparing a signal generated by the presentation system and a signal generated by a sample, wherein said presentation system comprises at least one copy of said target moiety or part thereof covalently attached to a domain of a scaffold wherein the domain is non-reactive to a binding partner specific to said target moiety.

La présente invention concerne un système de présentation et un procédé utilisés pour quantifier un groupe cible dans un échantillon qui est susceptible de contenir le groupe cible, le procédé comprenant l'utilisation d'une concentration spécifique ou la variation de la concentration d'un système de présentation afin de produire un point de comparaison ou une courbe de calibrage, pour obtenir un moyen pour comparer un signal produit par le système de présentation et un signal produit par un échantillon, ledit système de présentation comprenant au moins une copie dudit groupe cible ou d'une partie de celui-ci.

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