Agents for detecting and imaging cell death

A - Human Necessities – 61 – K

Patent

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Details

A61K 49/00 (2006.01) A61K 51/08 (2006.01)

Patent

CA 2722914

This invention relates to molecular imaging agents comprising an S78C mutant synaptotagmin I C2A domain. These agents may be useful in detecting or assessing cell death in vitro and in vivo, for example in tumours following cancer treat-ment.

La présente invention concerne des agents dimagerie moléculaires qui comprennent un domaine C2A de la synaptotagmine I dun mutant S78C. Ces agents peuvent savérer utiles dans la détection ou lévaluation de lapoptose in vitro et in vivo, par exemple dans des tumeurs après un traitement contre le cancer.

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