Agents for inhibiting the production of il-1.beta. and the...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) A61K 31/40 (2006.01) A61K 31/4015 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2165919

The pharmaceutical use of 1-cinnamoyl-2- pyrrolidinone derivatives having the activities to inhibit the production of IL-1.beta. and the release of TNF.alpha.. Those derivatives are useful in the treatment or prophylaxis of the diseases such as chronic rheumatism and sepsis.

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