Agents for potentiating the effects of antitumour agents and...

Details Agents for potentiating the effects of antitumour agents and... Agents for potentiating the effects of antitumour agents and...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/395 (2006.01) A61K 38/04 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2098198

2098198 9211034 PCTABS00014 Potentiating agents which enhance the efficacy of antineoplastic agents are disclosed. The potentiating agents disclosed are .alpha.-aryl-4-substituted piperidinoalkanol derivatives such as terfenadine, 11-(4-piperi-dylidene)-5H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridines such as Loratadine, and N-heterocyclyl-4-piperidinamines wherein said heterocyclic radical is an optionally substituted 1H-benzimidazol-2-yl or 3H-imidazo[4,5-b]pyridin-2-yl radical, such as astemizole.

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