C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 291/08 (2006.01) A61K 31/554 (2006.01)
Patent
CA 2620183
The present invention provides compounds of Formula I, (I) and salts, hydrates, solvates, complexes, and prodrugs thereof. The present invention further provides methods for synthesizing compounds of Formula I. The invention additionally provides pharmaceutical compositions comprising the compounds of Formula I and methods of using the pharmaceutical compositions of Formula I to treat and prevent disorders and diseases associated with the RyR receptors that regulate calcium channel functioning in cells.
Cette invention concerne des composés représentés par la formule I, (I) ainsi que des sels, des hydrates, des solvates, des complexes, et des promédicaments associés. Cette invention concerne également des méthodes permettant des synthétiser les composés représentés par la formule I. En outre, cette invention concerne des compositions pharmaceutiques comprenant les composés représentés par la formule I afin de prévenir et de traiter des troubles et des maladies associées aux récepteurs RyR qui régulent la fonction du canal calcique dans les cellules.
Cheng Zhen Zhuang
Deng Shixian
Landry Donald W.
Lehnart Stephan E.
Marks Andrew Robert
Gowling Lafleur Henderson Llp
The Trustees Of Columbia University In The City Of New York
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