Agents for producing the health-benefits of repeated exercise

A - Human Necessities – 61 – K

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Details

A61K 33/06 (2006.01) A61K 31/045 (2006.01) A61K 31/047 (2006.01) A61K 31/327 (2006.01) A61K 31/343 (2006.01) A61K 31/423 (2006.01) A61K 31/683 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2509007

A method for producing the health-benefits of exercise including (but not limited to) the treatment and prevention of cachexia, other wasting disorders, cancer, atherosclerosis, heart disease, acute or chronic autoimmune disease, chronic inflammatory disease, alcoholic hepatitis, non-alcoholic hepatitis, rheumatoid arthritis, osteoarthritis, type II diabetes, insulin insensitivity, Parkinson's disease, Alzheimer's disease, and any other condition caused or mediated by chronic oxygen radical damage or by chronic chemical toxicities using diacylglycerol or any of its' derivatives or analogues; phospholipids, including but not limited to phosphatidylinositol or any of its' derivatives or analogues; hydrogen peroxide; any lipid peroxide or lipid-soluble peroxide (including but not limited to short-, medium-, or long-chain fatty acid peroxides); any water soluble peroxide derivative which retains any of the reactive properties of the original peroxide; oxygen radical generating system capable of generating superoxide anions, hydrogen peroxides, hydroxyl radicals or any other chemical oxidant; one or two stressful exercise sessions of moderate to high intensity lasting for between 60 minutes and 90 minutes on any one day for a minimum of three non- consecutive days each week to up to seven days each week; calcium; calcium ionophores such as A23187 or thapsigargin and their derivatives; ethanol is provided.

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