C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/14 (2006.01) A61K 38/02 (2006.01) A61K 38/10 (2006.01) A61K 38/46 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) C07K 7/08 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2585247
Mimetics of a region of DynI including the serine residues S774 and S778 or phosphorylatable amino acids in homologous positions are provided. The mimetics exclude or do not imitating at least one phosphorylation site provided by the serine residues or phosphorylatable amino acids. The mimetics have application in the prophylaxis or treatment of neurological diseases or conditions. The mimetics can also be used to inhibit synaptic transmission.
Cousin Michael A.
Mccluskey Adam
Robinson Phillip J.
Children's Medical Research Institute
Cousin Michael A.
Gowling Lafleur Henderson Llp
Mccluskey Adam
Robinson Phillip J.
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