Agents for sequestering serum aging factors and uses therefore

A - Human Necessities – 61 – K

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A61K 8/97 (2006.01) A61Q 19/08 (2006.01) A61K 36/896 (2006.01)

Patent

CA 2555728

Methods for the prevention or treatment of disorders and complications of disorders resulting from cell damage caused by an aging-related isoform of NADH oxidase (arNOX) are described. The agent for such inhibition comprises processed various Narcissus tazzeta extracts, preferably IBR-DORMIN~, both alone and in combination with other inhibition agents, including ubiquinones like coenzyme Q. These agents bind arNOX and inhibit the ability of arNOX to generate reactive oxygen species, thereby decreasing the ability of arNOX to generate reactive oxygen species. Such agents, and their methods of administration, as extremely effective as part of anti-aging treatments.

L'invention porte sur des méthodes de prévention ou de traitement de troubles et de complications de troubles imputables à une lésion cellulaire provoquée par un isoforme lié au vieillissement de l'oxydase NADH (arNOX). Cet agent d'inhibition comprend divers extraits traités de Narcissus tazzeta, de préférence IBR-DORMIN®, à la fois seul et en combinaison avec d'autres agents d'inhibition, tels que des ubiquinones du type coenzyme Q. Ces agents se lient à arNOX et inhibent la capacité de arNOX à générer une espèce d'oxygène réactif. Ces agents, et leurs procédés d'administration, sont extrêmement efficaces dans le cadre de traitements antivieillissement .

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