Agents for the treatment of diseases caused by parasitic...

Details Agents for the treatment of diseases caused by parasitic... Agents for the treatment of diseases caused by parasitic...

C - Chemistry, Metallurgy

07

H

C07H 19/167 (2006.01) A61K 31/70 (2006.01) C07H 5/10 (2006.01) C07H 15/14 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2095214

The compounds 5'-deoxy-5'-(hydroxyethylthio)adenosine (HETA); 5'-deoxy-5'- (monofluoroethylthio)adenosine (MFE- TA); 5'-deoxy-5'-(chloroethylthio)adenosine (CETA); 5'-deoxy-5'- (bromoethylthio)adenosine (BETA); 5-deoxy-5-(monofluoroe- thylthio)ribose (MFETR); 5-deoxy-5-(chloroethylthio)ribose (CETR); 5-deoxy-5- (bromoethyithio)ribose (BETR) and 5-deoxy- 5-(hydroxyethylthio)ribose (HETR), are described as well as their uses in treating infections caused by 5'-deoxy-5'-methylthioad- enosine (MTA) phosphorylase-containing pathogenic microorganisms; in treating infections caused by 5-deoxy-5-methylthiori- bose (MTR) kinase-containing pathogenic microorganism; and for treating neoplastic diseases.

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