Agents targeting cd138 and uses thereof

Details Agents targeting cd138 and uses thereof Agents targeting cd138 and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2710453

Disclosed is a human murine chimeric antibody which substantially retains the antigen binding region of its murine counterpart and displays improved binding affinities to the antigen and/or more homogenous binding to target cells.

La présente invention concerne un anticorps chimérique murin/humain qui conserve sensiblement la région de liaison à l'antigène de son homologue murin et présente des affinités de liaison améliorées à l'antigène et/ou une liaison plus homogène aux cellules cibles.

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