Agents that disrupt cellular replication and their use in...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/20 (2006.01) C07C 275/44 (2006.01) C07C 335/08 (2006.01) C07C 335/12 (2006.01) C07C 335/14 (2006.01) C07C 335/16 (2006.01) C07D 211/52 (2006.01) C07D 215/40 (2006.01) C07D 217/06 (2006.01) C07D 243/08 (2006.01) C07D 307/68 (2006.01) C07D 317/66 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2646541

The present invention provides novel compounds that inhibit cell proliferation, in particular through the disruption of chromosome segregation and uses of these compounds for treating, ameliorating or preventing diseases, conditions or disorders benefiting from the antiproliferative consequences of the disruption of chromosome segregation, in particular hyperproliferative diseases.

La présente invention concerne de nouveaux composés qui inhibent la prolifération cellulaire, particulièrement par une perturbation de la ségrégation des chromosomes, et les utilisations de ces composés permettant de tirer profit des conséquences antiproliférantes de la perturbation de la ségrégation des chromosomes pour le traitement, l'amélioration ou la prévention de maladies, de pathologies, ou de troubles, en particulier de maladies hyperproliférantes.

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