Agents that regulate apoptosis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) A61K 38/46 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 9/22 (2006.01) C12N 15/11 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2446991

The present invention provides genes, nucleic acid sequences, proteins and amino acid sequences that are involved in the inhibition of apoptosis induction in cells. The invention also provides the RNA correlates of these genes and nucleic acid sequences. Further provided are isolated nucleic acid molecules that interact with the genes, nucleic acid sequences and RNA correlates disclosed herein, such that their inhibitory effect on apoptosis induction is lessened and, therefore, apoptosis induction is facilitated.

L'invention porte sur des gènes, des séquences d'acides nucléiques, des protéines et des séquences d'acides aminés impliqués dans l'inhibition de l'induction de l'apoptose dans des cellules. L'invention porte également sur les corrélats d'ARN de ces gènes, des séquences d'acides nucléiques, et des molécules isolées d'acides nucléiques et leurs corrélats d'ARN, dont l'effet inhibiteur sur l'induction de l'apoptose est réduit, ce qui a pour effet de favoriser l'induction de l'apoptose.

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