Agglomerated ion exchange particle bed and method

B - Operations – Transporting – 01 – J

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B01J 47/00 (2006.01) B01D 15/36 (2006.01)

Patent

CA 2620654

A liquid chromatography agglomerated bed comprising component A comprising (a) substrate particles and polymer chains (e.g. a condensation polymer) bound to the substrate particles and projecting therefrom, and (b) component B comprising substrate particles having external surfaces of opposite charge to that of the charged polymer chains, components A and B being bound at least in part by electrostatic forces between the component A charged polymer chains and the component B external surfaces to form in composite an agglomerated bed of ion exchange particles packed in a chromatography column.

L'invention concerne un lit de chromatographie liquide aggloméré qui comprend un composant A renfermant (a) des particules substrats et des chaînes de polymère (p.ex., un polymère de condensation) liées aux particules substrats et projetées depuis ces dernières, et (b) un composant B renfermant des particules substrats possédant des surfaces externes de charge opposée à celle des chaînes de polymère chargées, les composants A et B étant liés au moins en partie par des forces électrostatiques s'exerçant entre les chaînes de polymère chargées du composant A et les surfaces externes du composant B de sorte qu'ils forment, de manière composite, un lit aggloméré de particules d'échange ionique tassées dans un colonne de chromatographie.

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