C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/06 (2006.01) A61K 31/35 (2006.01) C07D 311/74 (2006.01) C07D 493/08 (2006.01) C07H 19/01 (2006.01) C12N 1/14 (2006.01) C12P 19/02 (2006.01) C12P 19/44 (2006.01)
Patent
CA 2057651
HOE 90/F 372 Abstract of the disclosure Agistatins, novel metabolites from Fusarium sp., a process for their preparation, and their use With the aid of a Fusaxium strain, it is possible to produce novel metabolites of the formula I below Image in which R1 is hydrogen or hydroxyl, R2 is hydroxyl or an oxo group, R3 is methoxy or hydroxyl or, together with R1, forms an ether bridge, and R4 is hydrogen or hydroxyl, R5 is hydrogen or, together with R4, is an additional bond, and R6 is hydrogen or, together with R3, is an additional bond. In particular, the metabolites are to be employed for inhibiting cholesterol biosynthesis.
Breiding-Mack Sabine
Coehrt Axel
Grabley Susanne
Granzer Ernold
Hutter Klaus
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Breiding-Mack Sabine
Coehrt Axel
Grabley Susanne
Granzer Ernold
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