Agonism of the 5ht2a receptor for treatment of...

A - Human Necessities – 61 – K

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A61K 31/138 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/15 (2006.01) A61K 31/166 (2006.01) A61K 31/343 (2006.01) A61K 31/381 (2006.01) A61K 31/405 (2006.01) A61K 31/445 (2006.01) A61K 31/4525 (2006.01) A61K 31/496 (2006.01) A61K 31/55 (2006.01) A61K 31/553 (2006.01) A61K 45/06 (2006.01) A61P 15/12 (2006.01)

Patent

CA 2494687

The present invention relates to a method for treating thermoregulatory disorders by administering compounds and compositions of compounds which by modulating 5HT levels activate the 5HT2a receptor. The invention also relates to therapy using 5HT1a antagonists and SRIs in combination and pharmaceutical compositions and products containing it.

Cette invention concerne une méthode de traitement de troubles de la thermorégulation consistant à administrer des composés et des compositions de composés qui, en modulant les niveaux de 5HT, activent le récepteur 5HT¿2a?. Cette invention porte également sur un traitement faisant intervenir des antagonistes du récepteur 5HT¿1a? combinés à des inhibiteurs de recaptage de la sérotonine (SRI) ainsi que sur des compositions pharmaceutiques et des produits contenant cette combinaison.

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