Agonist anti-trkc antibodies and methods using same

Details Agonist anti-trkc antibodies and methods using same Agonist anti-trkc antibodies and methods using same

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2551097

The invention concerns agonist anti-trkC antibodies, polypeptides, and polynucleotides encoding the same. The invention further concerns use of such antibodies, polypeptides and/or polynucleotides in the treatment and/or prevention of neuropathies, such as sensory neuropathies, including taxol- induced sensory neuropathy, cisplatin-induced sensory neuropathy, and pyridoxine-induced sensory neuropathy.

La présente invention concerne des anticorps anti-trkC agonistes, des polypeptides, et des polynucléotides codant pour ceux-ci. L'invention a également pour objet l'utilisation de ces anticorps, polypeptides et/ou polynucléotides dans le cadre du traitement et/ou de la prévention de neuropathies, telles que des neuropathies sensorielles, comprenant la neuropathie sensorielle induite par taxol, la neuropathie sensorielle induite par cisplatine, et la neuropathie sensorielle induite par pyridoxine.

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