A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 43/42 (2006.01) A01N 43/90 (2006.01) A01N 53/00 (2006.01) A01N 53/04 (2006.01) A01N 61/00 (2006.01) A61K 31/46 (2006.01) C07D 209/16 (2006.01) C07D 231/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 451/06 (2006.01) C07D 451/10 (2006.01) C07D 451/12 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 471/08 (2006.01) C07D 498/20 (2006.01) C07D 521/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/566 (2006.01) G01N 33/94 (2006.01)
Patent
CA 2456290
The present invention provides compositions and methods for controlling an helminth or arthropod pest. In a preferred embodiment of the invention provided herein, the compositions comprise compounds which alter the 5-HT3 receptor of the pest. Also claimed are various esters of N-methyl 8- azabicyclo[3.2.1]octan-3-ol (tropan-3-yl esters) and an assay for identifying and/or assessing a helminth and/or arthropod control compound by determining the ability of a candidate compound to modulate the activity of a helminth or arthropod 5-HT3 receptor.
La présente invention concerne des compositions et des procédés permettant de contrôler un parasite d'helminthe ou d'arthropode. Dans un mode de réalisation préféré de l'invention, les compositions contiennent des composés qui altèrent le récepteur 5Ht3 de l'animal nuisible. L'invention concerne également divers esters de N-méthyle 8-azabicyclo(3.2.1)octan-3-ol (esters de tropan-3-yle) et un dosage biologique permettant d'identifier et/ou d'évaluer un composé de contrôle d'helminthe et/ou d'arthropode en déterminant l'aptitude d'un composé candidat à moduler l'activité d'un récepteur 5-HT3 d'helminthe ou d'arthropode.
Liao Chunyan
Saubern Simon
Trowell Stephen Charles
Commonwealth Scientific And Industrial Research Organisation
Smart & Biggar
LandOfFree
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