Agonists and antagonists of the somatostatin receptor

Details Agonists and antagonists of the somatostatin receptor Agonists and antagonists of the somatostatin receptor

C - Chemistry, Metallurgy

07

K

C07K 5/02 (2006.01)

Patent

CA 2582384

The invention relates to substituted .beta.3-Phe-Trp-.beta.3 -Lys-beta-tri- peptides and derivatives thereof, a process for their preparation, pharmaceutical preparations which contain these compounds which are agonists/antagonists of somatostatin receptors, as active agents for the treatment of disorders which can be influenced by a modulation of somatostatin receptor activity, in particular somatostatin receptor sst4 activity, by the compounds of the invention.

L'invention concerne des ß3-Phe-Trp-ß3-Lys-béta-tri-peptides substitués et des dérivés de ceux-ci, un procédé de préparation de ceux-ci, des préparations pharmaceutiques contenant lesdits composés qui sont des agonistes/antagonistes des récepteurs de la somatostatine, utilisés comme agents actifs dans le traitement de troubles pouvant être influencés par une modulation de l'activité du récepteur de la somatostatine, en particulier l'activité du récepteur sst4 de la somatostatine, par les composés de l'invention.

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