C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 47/48 (2006.01) A61P 1/00 (2006.01)
Patent
CA 2688161
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition, including Crohn's disease and ulcerative colitis, and cancer.
La présente invention concerne de nouveaux peptides agonistes de guanylase cyclase-C et leur utilisation dans le traitement de maladies humaines comprenant les troubles gastro-intestinaux, une inflammation ou un cancer (par exemple, un cancer gastro-intestinal). Les peptides peuvent être administrés soit seuls, soit en combinaison avec un inhibiteur de phosphodiestérase dépendant de GMPc. Le trouble gastro-intestinal peut être classifié comme syndrome du côlon irritable, constipation ou acidité excessif, etc. La maladie gastro-intestinale peut être classée comme affection abdominale inflammatoire ou une autre affection gastro-intestinale, comprenant la maladie de Crohn et la colite ulcérative et un cancer.
Jacob Gary S.
Shailubhai Kunwar
Ridout & Maybee Llp
Synergy Pharmaceuticals Inc.
LandOfFree
Agonists of guanylate cyclase useful for the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Agonists of guanylate cyclase useful for the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Agonists of guanylate cyclase useful for the treatment of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1390821