Agroclavine and elymoclavine derivatives, process for their...

Details Agroclavine and elymoclavine derivatives, process for their... Agroclavine and elymoclavine derivatives, process for their...

C - Chemistry, Metallurgy

07

D

167/227, 260/206

C07D 457/02 (2006.01) A61K 31/48 (2006.01)

Patent

CA 2030340

Abstract of the Disclosure Disclosed are ergoline derivatives of formula I and their acid addition salts Image I in which R2 is halogen, C1-4-alkyl, C2-4-alkenyl, R6 is C2-6-alkyl, C3-6-alkenyl or C3-5-cycloalkyl-C1-2-alkyl and X is hydrogen, hydroxy or C1-6 acyloxy are described as well as their production and the pharmaceutical agents containing these compounds. The compounds exhibit a dopaminergic agonistic effect, and are useful in the treatment of Parkinson's disease.

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