Aib1, a novel steroid receptor co-activator

Details Aib1, a novel steroid receptor co-activator Aib1, a novel steroid receptor co-activator

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/033 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2295332

The invention features a substantially pure DNA which includes a sequence encoding a novel steroid receptor co-activator which is overexpressed in breast cancer cells, diagnostic assays for steroid hormone- responsive cancers, and screening assays to identify compounds which inhibit an interaction of the co-activator with the steroid hormone.

Cette invention concerne un ADN sensiblement pur qui comprend une séquence codant un nouveau co-activateur du récepteur stéroïdien qui est surexprimé dans des cellules de carcinome mammaire, des dosages de diagnostic destinés à rechercher les cancers réagissant à l'hormone stéroïdienne, et des dosages de criblage permettant d'identifier des composés qui inhibent une interaction du co-activateur avec l'hormone stéroïdienne.

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