Airway administration of activated protein c in inflammatory...

Details Airway administration of activated protein c in inflammatory... Airway administration of activated protein c in inflammatory...

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2612597

The present invention provides methods for the local treatment of acute and chronic extravascular pulmonary fibrin deposition and/or reducing unwanted effects associated with systemic administration of anticoagulants to a subject via airway administration to the subject by intratracheal, intrabronchial or intraalveolar routes of human activated protein C or biologically active derivatives thereof .

La présente invention a trait à des procédés pour le traitement local de dépôt de fibrines pulmonaires extravasculaires aigu et chronique et/ou la réduction d'effets indésirables associés à l'administration systémique d'anticoagulants à un sujet par l'administration aux voies aériennes au sujet par des voies intratrachéale, intrabronchique ou intraalvéolaire d'anticoagulants ou de leurs dérivés bioactifs.

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