Airway administration of tissue factor pathway inhibitor in...

Details Airway administration of tissue factor pathway inhibitor in... Airway administration of tissue factor pathway inhibitor in...

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2612646

The present invention provides methods for the local treatment of acute and chronic extravascular pulmonary fibrin deposition and/or reducing unwanted effects associated with systemic administration of natural anticoagulants to a subject via airway administration to the subject by intratracheal, intrabronchial or intraalveolar routes of natural anticoagulants or biologically active derivatives thereof.

L'invention concerne des méthodes de traitement local du dépôt de fibrine, aigu et chronique, dans l'espace pulmonaire extravasculaire et/ou de réduction des effets indésirables associés à l'administration par voie générale d'anticoagulants naturels, qui consistent à administrer à un sujet des anticoagulants ou des dérivés biologiquement actifs de ceux-ci par voie aérienne (intratrachéale, intrabronchiale ou intra-alvéolaire).

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