Akap18 delta, a novel splicing variant of a protein kinase a...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2497254

The invention relates to a nucleic acid sequence coding for a protein kinase A anchor protein, to the use of said nucleic acid sequence in a fusion protein, to a method for determining the interaction of the protein kinase A anchor protein with regulatory sub-units of the protein kinase A, and to a method for identifying cell-permeable substances.

L'invention concerne une séquence nucléotidique codant pour une protéine d'ancrage de la protéine kinase A, une utilisation de cette séquence nucléotidique dans une protéine de fusion et un procédé de détermination de l'interaction de la protéine d'ancrage de la protéine kinase A avec des sous-unités régulatrices de la protéine kinase A. L'invention concerne également un procédé d'identification de substances pouvant pénétrer dans les cellules. ? ¿

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