Akt nucleic acids, polypeptides, and uses thereof

Details Akt nucleic acids, polypeptides, and uses thereof Akt nucleic acids, polypeptides, and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/7088 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2343074

The present invention relates to human Akt3 proteins and polypeptides. The invention also relates to isolated nucleic acids encoding human Akt3, to vectors containing them and to their therapeutic uses, in particular for gene therapy. Expression of Akt3 inhibits cell death associated with hypoxia, apoptosis or necrosis.

La présente invention porte sur des protéines et polypeptides Akt3 humains, ainsi que sur des acides nucléiques isolés codant l'Akt3 humain, sur des vecteurs les contenant et sur leurs utilisations thérapeutiques, notamment en thérapie génique. L'expression d'Akt3 inhibe la mort cellulaire associée à l'hypoxie, l'apoptose ou la nécrose.

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