Al-1 neurotrophic factor, a ligand for an eph-related...

Details Al-1 neurotrophic factor, a ligand for an eph-related... Al-1 neurotrophic factor, a ligand for an eph-related...

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 16/22 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 15/13 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2203888

The present invention provides nucleic acids encoding AL-1 protein, as well as AL-1 protein produced by recombinant DNA methods. Such AL-1 protein is useful in preparing antibodies and antagonists and in diagnosing and treating various neuronal disorders and disorders or conditions associated with angiogenesis.

Cette invention présente des acides nucléiques codant une protéine de l'AL-1, ainsi qu'une protéine AL-1 produite par des méthodes de génie génétique. Cette protéine AL-1 s'avère utile tant pour préparer des anticorps et des antagonistes que pour diagnostiquer et traiter divers troubles neuronaux ainsi que des troubles ou des états pathologiques associés à l'angiogenèse.

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