Al-2 neurotrophic factor

Details Al-2 neurotrophic factor Al-2 neurotrophic factor

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 47/48 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01) C07K 16/00 (2006.01) C07K 16/22 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2250431

The present invention provides nucleic acids encoding AL-2 protein, as well as AL-2 protein produced by recombinant DNA methods. Such AL-2 protein and nucleic acid are useful in preparing antibodies and antagonists and in diagnosing and treating various neuronal disorders and disorders or conditions associated with angiogenesis.

L'invention concerne des acides nucléiques codant pour la protéine Al-2, ainsi que la protéine AL-2 produite par des méthodes faisant appel à de l'ADN de recombinaison. Ces protéines AL-2 et ces acides nucléiques sont utiles pour préparer des anticorps et des antagonistes et pour diagnostiquer et traiter différentes troubles neurologiques, ainsi que pour traiter les troubles et affections pathologiques associés à l'angiogénèse.

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