Albumin purification

Details Albumin purification Albumin purification

C - Chemistry, Metallurgy

07

K

530/15.06

C07K 14/765 (2006.01) C07K 1/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2022165

There is provided in accordance with the practice of this invention a process for separating albumin from an impure protein fraction containing albumin. Contaminants, in an aqueous solution of the impure protein fraction containing albumin, are precipitated from the solution at a pH of from about 4.5 to about 4.7. Additional contaminants that remain soluble are bound to an anion-exchange resin. After the precipitated and anion-exchange-bound contaminants are removed from the albumin-containing solution, the pH of the solution is adjusted to from about 4.7 to about 6.1, and additional contaminants are precipitated. Further contaminants are then bound to an anion-exchange resin, and these precipitated and anion-exchange-bound contaminants are removed from the albumin-containing solution.

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