Alcohol-free transdermal insulin composition and processes...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/28 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 47/06 (2006.01) A61K 47/12 (2006.01) A61K 47/14 (2006.01) A61K 47/16 (2006.01) A61K 47/20 (2006.01) A61K 47/30 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2523864

The instant invention is directed toward a dermal delivery system composition comprising an aqueous base vehicle including American Emu oil, Isopropyl Palmitate (PROTACHEM IPP), PEG-8 (a polyethylene glycol available under the tradename PROTACHEM 400), methylsulfonylmethane (MSM)and SEPIGEL 305 (a combination including polyacrylamide/C13-C14 Iso-paraffin and LAURETH 7, in combination with a therapeutically effective amount of at least one species of insulin, and to processes for the manufacture and use thereof.

L'invention concerne une composition pour un système d'administration dermique qui comprend un véhicule à base aqueuse contenant de l'huile d'émeu d'Amérique, du palmitate d'isopropyle (PROTACHEM IPP), du PEG-8 (un polyéthylèneglycol disponible sous l'appellation commerciale PROTACHEM 400), du méthylsulfonylméthane (MSM) et du SEPIGEL 305 (une combinaison à base de polyacrylamide/d'isoparaffine C¿13?-C¿14? et de LAURETH 7), en combinaison avec une dose efficace sur le plan thérapeutique d'au moins une espèce d'insuline. L'invention concerne également des procédés de production et d'utilisation de ladite composition.

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