Alcohol-resistant sustained-release oral pharmaceutical form...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/50 (2006.01) A61K 9/16 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2739018

The invention relates to an oral pharmaceutical form containing microgranules for the sustained release of at least one active principle, including a neutral carrier that is insoluble in water or in an alcoholic solution, or a neutral carrier rendered insoluble in water or an alcoholic solution, comprising at least one first mounting layer containing at least one active principle and optionally a pharmaceutically acceptable binding agent, wherein the assembly comprises at least one coating containing at least one hydrophobic polymer.

L'invention concerne une forme pharmaceutique orale à base de microgranules à libération prolongée d'au moins un principe actif, comprenant un support neutre insoluble dans l'eau ou dans une solution alcoolique, ou un neutre rendu insoluble dans l'eau ou dans une solution alcoolique, comportant au moins une première couche de montage comprenant au moins un principe actif et éventuellement un agent liant pharmaceutiquement acceptable; l'ensemble comportant au moins un enrobage à base d'au moins un polymère hydrophobe.

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