Aldh-2 inhibitors in the treatment of psychiatric disorders

Details Aldh-2 inhibitors in the treatment of psychiatric disorders Aldh-2 inhibitors in the treatment of psychiatric disorders

A - Human Necessities

61

K

A61K 31/352 (2006.01) A61K 31/422 (2006.01) A61K 31/4245 (2006.01) A61K 31/427 (2006.01) A61K 31/496 (2006.01) A61K 31/661 (2006.01) A61K 31/69 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2704981

Disclosed are isoflavone derivatives having the structure of Formula (I) which are useful as ALDH-2 inhibitors for use treating in mammals suffering from psychiatric disorders such as, for example, depression, generalized anxiety, social phobia, panic disorder, and sleep disorders.

L'invention concerne des dérivés d'isoflavone ayant la structure de formule (I) qui sont utiles comme inhibiteurs ALDH-2 pour une utilisation dans le traitement de mammifères souffrant de troubles psychiatriques tels que, par exemple, la dépression, l'anxiété généralisée, la phobie sociale, la panique et les troubles du sommeil.

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