C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 31/02 (2006.01) A61K 47/48 (2006.01) C08B 31/00 (2006.01) C08B 31/18 (2006.01) C08B 33/02 (2006.01) C08B 35/02 (2006.01)
Patent
CA 2504799
The invention relates to aldonic acid esters of starch fractions or starch fraction derivatives which are selectively oxidised on the reducing chain end to form aldonic acids, and to solids and solutions containing said aldonic acid esters. The invention also relates to methods for producing said aldonic acid esters, to methods for producing pharmaceutical active ingredients coupled to polysaccharides or polysaccharide derivatives on free amino functions, and to pharmaceutical active ingredients thus obtained.
La présente invention concerne des esters d'acide aldonique de fractions d'amidon, ou de dérivés de fractions d'amidon, oxydés de manière sélective à l'extrémité réduite de la chaîne pour donner de l'acide aldonique, des substances solides et des solutions qui contiennent ces esters d'acide aldonique. L'invention a également pour objet des procédés pour préparer ces esters d'acide aldonique, des procédés pour préparer des principes actifs pharmaceutiques couplés à des polysaccharides ou à des dérivés de polysaccharides au niveau de groupes amino libres, et les principes actifs pharmaceutiques ainsi obtenus.
Fetherstonhaugh & Co.
Supramol Parenteral Colloids Gmbh
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