Aldose reductase inhibition by 1-(4-chlorobenzoyl)-5-...

A - Human Necessities – 61 – K

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A61K 31/405 (2006.01)

Patent

CA 1162856

-8- AHP1955 ABSTRACT OF THE DISCLOSURE Disclosed are new methods of using 1-(4-chlorobenzoyl-5-methoxy- 2-methyl-1H-indole-3-acetic acid, or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications as- sociated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.

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