Aldosterone blocker therapy to prevent or treat...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/585 (2006.01) A61K 31/13 (2006.01) A61K 31/4152 (2006.01) A61K 31/437 (2006.01) A61K 31/5513 (2006.01) A61K 31/57 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2478473

A method of preventing or treating an inflammation-related disorder such as myocarditis, cardiomyopathy, vasculitis, and Behcet~s disease in a subject, comprising treating the subject with a therapeutically-effective amount of an aldosterone blocker sufficient to alter the expression of one or more expression products involved, directly or indirectly, in the regulation of inflammation or cardiac remodeling in the subject.

L'invention concerne une méthode permettant de prévenir ou des traiter des troubles associés à une inflammation, tels que la myocardite, la cardiomyopathie, la vascularite et la maladie de Behçet chez un sujet. Ladite méthode consiste à traiter le sujet avec une quantité thérapeutiquement efficace suffisante d'un bloqueur d'aldostérone pour modifier l'expression d'un ou plusieurs produit(s) d'expression impliqué(s) directement ou indirectement dans la régulation d'une inflammation ou d'un remodelage cardiaque chez ledit sujet.

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