Alkeneamidocephalosporin esters

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 501/20 (2006.01) A01N 43/86 (2006.01) A61K 31/345 (2006.01) A61K 31/54 (2006.01) A61K 31/545 (2006.01) C07D 501/04 (2006.01) C07D 501/22 (2006.01) C07D 501/24 (2006.01) C07D 501/34 (2006.01) C07D 501/36 (2006.01) C07D 501/46 (2006.01) C07D 501/59 (2006.01) C07D 277/30 (2006.01) C07D 501/18 (2006.01)

Patent

CA 1269655

A B S T R A C T An oral antibacterial, 7-beta-[(Z)-2- (2-aminothiazol-4-yl)-2-alkenoylamino]-3-cephem- 4-carboxylic acid pharmaceutically acceptable ester represented by the following formula: Image (wherein R is amino or protected amino, R1 is straight, branched, or cyclic alkyl optionally substituted by alkoxy, R2 is hydrogen or a 3-substituent of Cephalosporins, R3 is a pharmaceutically acceptable ester group and X is sulfur or sulfinyl)

505441

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