Alkenyltetrazole derivatives

C - Chemistry – Metallurgy – 07 – D

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260/312, 260/304

C07D 257/04 (2006.01) C07D 493/08 (2006.01)

Patent

CA 1332607

Abstract Tetrazole derivatives represented by the formula: Image wherein R is naphthyl or phenyl optionally substituted by phenyl, lower alkyl, halogen, lower alkoxy, hydroxy or acetoxy; X is methylene, dimethylmethylene or oxygen; n is an integer of 0 or 1; and p and r each is an integer of 0 or 1 and q is an integer of 1 or 2 provided that p + q + r = 2; or a tautomer in tetrazole ring and a pharmaceutically acceptable salt thereof, which are useful as TXA2 receptor antagonist.

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