Alkyl amino-glucopyranoside derivative and process for...

Details Alkyl amino-glucopyranoside derivative and process for... Alkyl amino-glucopyranoside derivative and process for...

C - Chemistry, Metallurgy

07

H

260/230.58

C07H 15/04 (2006.01) C07H 13/12 (2006.01)

Patent

CA 1044228

ABSTRACT OF THE DISCLOSURE Alkyl amino-glucopyranoside derivative including alkyl N-carbamyl-N'-(2-chloroethyl)-N'-nitroso-6-amino-6- deoxy-D-glucopyranoside, alkyl N-carbamyl-N'-(2-chloroethyl)- N'-nitroso-2-amino-2-deoxy-D-glucopyranoside, and alkyl di- N,N'-[N-(2-chloroethyl)-N-nitroso carbamyl]-2,6-di-amino-2, 6-di-deoxy-D-glucopyranoside, is disclosed. The derivative exhibits marked antitumor activity while not having diabet- ogenic activity and bone marrow toxicity. The derivative is further water soluble and free from antibacterial activity.

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