A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/765 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/77 (2006.01) A61K 31/775 (2006.01) A61M 11/00 (2006.01) A61M 15/00 (2006.01)
Patent
CA 2435573
A method and composition for treatment and prophylaxis of snoring, sleep apnea or sudden infant death syndrome and for improvement of nasal breathing in mammals by nasal and/or pharyngeal administration of tyloxapol or a related alkylaryl polyether alcohol polymer. A spray, liquid or solid composition comprising from about 0.01 to about 20 % (w/v), equivalent to about 100 µg/ml to about 200 mg/ml, or tyloxapol or another alkylaryl polyether alcohol polymer alone or in admixture with pharmaceutically acceptable excipients and additives. The composition is administered as a spray, liquid, liquid drops, lozenges or powder suitable for nasal and/or pharyngeal application.
L'invention concerne un procédé et une composition permettant de traiter et de prévenir le ronflement, l'apnée du sommeil ou le syndrome de la mort subite du nourrisson, et d'améliorer la respiration nasale chez les mammifères par administration, par voie nasale ou pharyngienne, de tyloxapol ou d'un polymère alkylaryl polyéther alcool. Une composition vaporisée, liquide ou solide, comprenant environ 0,01 à environ 20 % (w/v), soit d'environ 100 µg/ml à environ 200 mg/ml, de tyloxapol ou autre polymère alkylaryl polyéther alcool, seul ou mélangé à des excipients et additifs pharmaceutiquement acceptables. La composition est administrée vaporisée, liquide, ou sous forme de gouttelettes liquides, de pastilles ou de poudre que l'on peut administrer par voie nasale et/ou pharyngienne.
Gowling Lafleur Henderson Llp
Hofmann Thomas
Summamus Pharma Inc.
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