Alkyl carbamate-substituted butyrolactones serving as lipase...

C - Chemistry – Metallurgy – 07 – D

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C07D 305/12 (2006.01) A61K 31/335 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2560446

The invention relates to substituted .beta.-lactones (oxetanones) of general formula (I), in which R1, R2 and n have the meanings cited in the description, and to medicaments, which contain these compounds and which have a pancreas lipase-inhibiting effect. The invention also relates to a method for producing the compounds of formula (I) and to intermediate products of this method.

L'invention concerne des .beta.-lactones substituées (oxétanones) de formule générale (I), dans laquelle R1, R2 et n ont la signification mentionnée dans la description, ainsi que des médicaments contenant lesdits composés, à effet inhibiteur de la lipase pancréatique. L'invention concerne également un procédé permettant de produire des composés de formule (I) et des produits intermédiaires dudit procédé.

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