Alkyl derivatives of prostanoic acids and preparation thereof

Details Alkyl derivatives of prostanoic acids and preparation thereof Alkyl derivatives of prostanoic acids and preparation thereof

C - Chemistry, Metallurgy

07

C

260/235.01, 260/

C07C 69/74 (2006.01) C07C 177/00 (1980.01)

Patent

CA 1054150

Abstract of the Disclosure 15- And/or 16-alkyl derivatives of 9,15-dioxygenated prost-13-enoic, prosta-4,13-dienoic and prosta-5,13-dienoic acid, lower alkyl esters thereof and homologs thereof, as well as a process for preparing these derivatives are disclosed. The compounds possess hypotensive, anti- hypertensive, bronchospasmolytic, gastric acid secretion inhibiting, abortifacient, estrus synchronizing and ovulation regulating properties. The compounds also inhibit the aggregation of platelets and promote the disaggregation of aggregated platelets. Methods for their use are also disclosed. - 1 -

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