Alkyl ether derivatives or their salts

Details Alkyl ether derivatives or their salts Alkyl ether derivatives or their salts

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4525 (2006.01) A61K 31/4535 (2006.01) A61P 25/02 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C07D 207/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2464358

An alkyl ether derivative represented by the general formula: (see formula 1) wherein each of R1 and R2 represents one or more groups selected from a hydrogen atom, a halogen atom, an alkyl group, an aryl group, an aralkyl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group, an alkenyl group, an alkenyloxy group, an amino group, an alkylsulfonyl group, an arylsulfonyl group, a carbamoyl group, a heterocyclic group, a hydroxyl group, a carboxyl group, a nitro group, an oxo group and the like; R3 is an alkylamino group, an amino group, a hydroxyl group or the like; the ring A is a 5-membered or 6-membered heteroaromatic ring or a benzene ring; each of m and n is an integer of 1 to 6; and p is an integer of 1 to 3, or its salt has activity to protect neurons, activity to accelerate nerve regeneration and activity to accelerate neurite extension and hence is useful as a therapeutic agent for diseases in central and peripheral nerves.

L'invention concerne des dérivés d'éther d'alkyle représentés par la formule générale [1], ou des sels de ceux-ci. Ces dérivés ou sels ont une fonction de protection des nerfs, d'accélération de la régénération des nerfs, de potentialisation de la croissance axonale, et sont utiles en tant que médicaments pour des maladies du système nerveux périphérique et central. Dans cette formule générale (I), R?1¿ et R?2¿ représentent chacun hydrogène, halogéno, alkyle, aryle, aralkyle, alcoxy, aryloxy, alkylthio, arylthio, alcényle, alcényloxy, amino, alkylsulfonyle, arylsulfonyle, carbamoyle, un groupe hétérocyclique, hydroxyle, carboxyle, nitro, oxo ou similaire. R?3¿ représente alkylamino, amino, hydroxyle ou similaire. A représente un hétérocycle aromatique à 5 ou 6 chaînons ou un noyau de benzène, m et n représentent chacun un nombre entier compris entre 1 et 6, et p représente un nombre entier compris entre 1 et 3.

Affiliated with

Also associated with

Rating

Alkyl ether derivatives or their salts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Alkyl ether derivatives or their salts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Alkyl ether derivatives or their salts will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2068692