Alkyl ketones as potent anti-cancer agents

Details Alkyl ketones as potent anti-cancer agents Alkyl ketones as potent anti-cancer agents

C - Chemistry, Metallurgy

07

C

C07C 323/25 (2006.01) A61K 31/00 (2006.01) C07C 225/06 (2006.01) C07C 233/05 (2006.01) C07C 233/31 (2006.01) C07C 245/14 (2006.01) C07C 271/12 (2006.01) C07C 271/18 (2006.01) C07C 271/22 (2006.01) C07C 323/22 (2006.01) C07C 323/48 (2006.01) C07C 323/52 (2006.01) C07C 323/58 (2006.01) C07C 323/59 (2006.01) C07C 323/60 (2006.01)

Patent

CA 2336108

Novel alkyl ketone compounds having potent cytotoxic activity are described as antitumor agents and are particularly effective against leukemia and breast tumor cells. The compounds of the invention have formula (I), wherein R1-R4, X and p have the meanings given in the description.

L'invention concerne de nouveaux composés à base d'alkyl cétones ayant une puissante activité cytotoxique, qui tiennent lieu d'agents antitumoraux et qui sont particulièrement efficaces contre la leucémie et contre les cellules des tumeurs du sein. Les composés considérés sont représentés par la formule (I). Pour les besoins de ladite formule, R¿1?-R¿4?, X et p sont tels que décrits dans le corps de l'invention.

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