Alkyl or alkoxy substituted s-heterocyclic retinoids

C - Chemistry – Metallurgy – 07 – D

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C07D 337/08 (2006.01) A61K 31/38 (2006.01) C07D 333/54 (2006.01) C07D 335/06 (2006.01)

Patent

CA 2093577

Compounds of the formula Image in which X represents -S-, -SO- or -SO2-; R1 represents C7-10-alkyl or C1-10-alkoxy; R2 represents a residue of the formula Image R3 represents carboxy or lower-alkoxycarbonyl; and n represents 1, 2 or 3; and salts of carboxylic acids of formula I can be used as medicaments, e.g, for the treatment of autoimmune diseases and diseases having a strong immunological component, such as psoriasis.

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