Alkyl substituted fluorescent compounds and conjugates

Details Alkyl substituted fluorescent compounds and conjugates Alkyl substituted fluorescent compounds and conjugates

C - Chemistry, Metallurgy

07

J

530/17, 260/212,

C07J 41/00 (2006.01) C07C 63/68 (2006.01) C07D 311/82 (2006.01) G01N 33/52 (2006.01) G01N 33/533 (2006.01)

Patent

CA 1159823

ABSTRACT OF THE DISCLOSURE Fluorescent antigen conjugates are provided comprising antigens covalantly bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H- xanthen-3-one, wherein the 1- and 8-positions are unsub- stituted. Also provided are novel fluorescent compounds absorbing at wavelengths in excess of 500nm, having active functionalities for linking to the antigen. Finally, methods are provided for analyzing antigens in serum, whereby serum interference is avoided.

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