Alkyl substituted heterocycles

Details Alkyl substituted heterocycles Alkyl substituted heterocycles

C - Chemistry, Metallurgy

07

D

C07D 211/18 (2006.01) A61K 31/395 (2006.01) C07D 211/22 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/32 (2006.01) C07D 211/62 (2006.01) C07D 295/13 (2006.01) C07D 401/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2123636

ABSTRACT ALKYL SUBSTITUTED HETEROCYCLES The present invention concerns the novel alkyl substituted heterocycles of formula I, set out below, wherein Q, Q1, Q2 and R have the values defined herein, which antagonize the pharmacological actions of one of the endogenous neuropeptide tachykinins at the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the alkyl substituted heterocycles for use in such treatment, methods for their use, and processes and novel intermediates for their manufacture. Image I

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